Cell Reports Medicine
20 June 2023
Profiling the metabolome of uterine fluid for early detection of ovarian cancer
Pan Wang1,2,3,4,7 ,Jihong Ma1,2,3,4,7 ,Wenjing Li1,2,3,4,7 ,Qilong Wang1,5,6 ,Yinan Xiao1,2,3,4 ,Yuening Jiang1,2,3,4 ,Xiaoyang Gu1,2,3,4 ,Yu Wu1,2,3,4 ,Suwei Dong5,6 ,Hongyan Guo1,2,3,4,* ,Mo Li1,2,3,4,8,*
1 Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China
2 National Clinical Research Center for Obstetrics and Gynecology (Peking University Third Hospital), Beijing 100191, China
3 Key Laboratory of Assisted Reproduction (Peking University), Ministry of Education, Beijing 100191, China
4 Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology (Peking University Third Hospital), Beijing 100191, China
5 State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China
6 Department of Chemical Biology, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China
7 These authors contributed equally
8 Lead contact
10.1016/j.xcrm.2023.101061
Wang et al. (101061) report the metabolic features in uterine fluid of gynecological patients and establish a noninvasive approach for early diagnosis of ovarian cancer. Originating from the cancerous niche of one ovary, abnormal metabolites flow through the fallopian tube and are pooled in uterine cavity. The crane is a metaphor denoting the metabolomics analysis strategy of uterine fluid from the patients.
Anhui Province Academy of Science and Technology, No. 128,Wanshui Road, Hi-Tech Zone, Hefei City, Anhui Province, China
+86 17354022649
service@sondii.com
IPv6 network supported
Our hours
Mon 11/21 - Wed 11/23: 9 AM - 8 PM
Thu 11/24: closed - Happy Thanksgiving!
Fri 11/25: 8 AM - 10 PM
Sat 11/26 - Sun 11/27: 10 AM - 9 PM
(all hours are Eastern Time)
